https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46962 Il22−/−) mice. CS-induced airway remodelling and emphysema-like alveolar enlargement did not occur in Il22−/− mice. Il22−/− mice had improved lung function in terms of airway resistance, total lung capacity, inspiratory capacity, forced vital capacity and compliance. These data highlight important roles for IL-22 and its receptors in human COPD and CS-induced experimental COPD.]]> Mon 12 Dec 2022 14:27:30 AEDT ]]> Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48427 Fri 26 Apr 2024 13:31:04 AEST ]]>